This database was made possible by a collaboration between the VIA research group and the Weiss Lab, with support from the Cornell University Center for Vertebrate Genomics and the Cornell University Institute of Biotechnology. These data are provided to assist the development and validation of tumor volume and growth measurement algorithms in small mammals imaged using micro-CT.

The database consists of an image set of longitudinal micro-CT scans on four live mice. These mice over-express the ribonucleotide reductase (RNR), an enzyme essential for making nucleotides, and develop lung tumors around 11 or 12 months of age. These in vivo scans were acquired using a GE eXplore CT 120 micro-CT scanner and were reconstructed at 50 x 50 x 50 µm3 resolution. Respiratory gating was performed to acquire imaging during the quiescent/refractory period after each breath to minimize motion artifacts. The mice were scanned a minimum of three times each, with at least three weeks between scans. There are a total of 19 scans included in the longitudinal study. Half of the scans included a calibration phantom with materials simulating air (-1000 HU), water (0 HU), and bone (2500 HU). In addition to the set of longitudinal scans, images of post-mortem scans of three mice are also included. All images are freely available and may be downloaded from the website. Additional details about these data and associated analyses are available in the following paper: --Paper citation here--

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