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Hip DysplasiaOsteoarthritis is the leading cause of adult disability in the United States. Approximately 40% of idiopathic osteoarthritis (OA) cases can be attributed to developmental dysplasia of the hip (DDH). While the endstage OA has been the subject of much research, little is known, about the early postnatal development of the dysplastic hip. The objective of this research is to quantitatively describe the temporal development of normal and dysplastic hips. A canine model of hip development is used in conjunction with a longitudinal study design. Noninvasive evaluation of the hip joint using computed tomography was performed periodically during growth. Image analysis techniques are being used to quantify temporal changes in femoral head ossification size, shape and density distribution. Measures predictive of developmental abnormalities will enable clinicians to diagnose and treat previously undetected cases of DDH. Characteristic features of dysplastic hips will also enable clinicians to identify and proactively treat hips at risk for developing OA. |